Dess-Martin Oxidation

2016-09-12 The Dess-Martin Periodinane (DMP), a hypervalent iodine compound, offers selective and very mild oxidation of alcohols to aldehydes or ketones.The oxidation is performed in dichlor

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National Day Holiday 2014

2014-09-29 We will be on National Day holiday from Oct. 01, 2014 to Oct. 07, 2014.

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Synthesis and c-Met Kinase Inhibition

2014-08-26 c-Met is a unique receptor tyrosine kinase(RTK) structurally distinct from other RTK families. It is the cell surface receptor for hepatocyte growth factor(HGF) and is normally exp

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One-pot synthesis of stilbenes

2014-07-22 The concept of performing more than one transformation in a single vessel, or developing one-pot processes, can generate less waste, reduce work-up procedures, avoid separation of

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A stereoselective synthesis of (S)-dapoxetine

2014-06-23 Recently, it has been suggested that premature ejaculation (PE) might be associated with perturbations in serotonergic 5-hydroxytryptamine (5-HT) neurotransmission. It has been pro

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N-substituted morpholino benzamide derivatives

2014-05-15 A mixture of 4-chloro benzonitrile and morpholine was subjected to microwave irradiation in solvent free condition to give 4-morpholino benzonitrile. Partial hydrolysis of 4-morpho

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Synthesis of Pyrrolo[1,2-b]pyridazine

2014-04-09 Pyrrolo[1,2-b]pyridazine is a N-bridgehead aromatic heterocycle containing two nitrogen atoms, formally obtained by the condensation of pyridazine and pyrrole. The numbering of the

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Selective Synthesis of Substituted Imidazoles

2014-03-12 1-Substituted 2-,4-,and 5-cyanoimidazoles were produced by reaction of 3-cyclohexyl or 3-p-tolylimidazole 1-oxide and trimethylsilyl cyanide in the presence of triethylamine. The p

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Synthesis of 2-Substituted Thiazoles

2014-02-26 2-(Trimethylsilyl)thiazole (2-TST)4 is used as a stable and convenient substitute for 2-lithiothiazole for introducing various substituents at C-2 of the thiazole ring. Reactions o

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Chinese Spring Festival 2014

2014-01-08 We will be on Chinese Spring Festival from Jan. 30, 2014 to Feb. 07, 2014

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